2022
Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age Journal Article
In: Diabetes, vol. db210536, 2022.
Unraveling and Targeting Myocardial Regeneration Deficit in Diabetes Journal Article
In: Antioxidants, vol. 11, no. 2, pp. 208, 2022.
2021
From Spheroids to Organoids: The Next Generation of Model Systems of Human Cardiac Regeneration in a Dish Journal Article
In: Int. J. Mol. Sci., vol. 22, no. 24, pp. 13180, 2021.
Cardiac stem cell therapy towards the clinic: The way forward re-starts from within Journal Article
In: Int J Cardiol, vol. S0167-5273(21)01573-4, 2021.
In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes Journal Article
In: Communications Biology, vol. 4, no. 1146, 2021.
WIND (Workflow for pIRNAs aNd beyonD): a strategy for in-depth analysis of small RNA-seq data Journal Article
In: F1000Research, vol. 10, no. 1, 2021, ISSN: 20461402.
Physical Exercise and Cardiac Repair: The Potential Role of Nitric Oxide in Boosting Stem Cell Regenerative Biology Journal Article
In: Antioxidants, vol. 10, no. 7, pp. 1002, 2021.
The baby and the bath water: adult cardiac stem cells revisited Journal Article
In: European Heart Journal, no. ehab335, 2021.
2020
In: International Journal of Molecular Sciences, vol. 21, no. 7927, 2020.
Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease Journal Article
In: Cells, vol. 9, no. 6, pp. 1558, 2020.
Unravelling the Biology of Adult Cardiac Stem Cell-Derived Exosomes to Foster Endogenous Cardiac Regeneration and Repair Journal Article
In: Int. J. Mol. Sci., vol. 21, no. 10, pp. 3725, 2020.
Atrial myxomas arise from multipotent cardiac stem cells Journal Article
In: Eur Heart J, vol. 41, iss. 45, pp. 4332-4345, 2020, ISSN: 1522-9645 (Electronic) 0195-668X (Linking).
Atrial myxomas arise from multipotent cardiac stem cells Journal Article
In: European Heart Journal, pp. 1-16, 2020, ISSN: 0195-668X, (ehaa156).
2019
Heterogeneity of Adult Cardiac Stem Cells Book Chapter
In: Birbrair, A (Ed.): Stem Cells Heterogeneity in Different Organs, pp. 141-178, Springer International Publishing, Cham, 2019, ISBN: 978-3-030-24108-7.
Role of c-Kit in Myocardial Regeneration and Aging Journal Article
In: Frontiers in Endocrinology, vol. 10, no. 371, 2019, ISSN: 1664-2392.
c-kit Haploinsufficiency impairs adult cardiac stem cell growth, myogenicity and myocardial regeneration Journal Article
In: Cell Death & Disease, vol. 10, no. 436, 2019.
Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon? Journal Article
In: Oxidative Medicine and Cellular Longevity, vol. 2019, no. 5813147, pp. 19, 2019.
2018
MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus Journal Article
In: Diabetes, vol. 67, no. 10, 2018, ISSN: db171434.
In: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 119, pp. 10-18, 2018, ISSN: 0022-2828.
Kit(cre) knock-in mice fail to fate-map cardiac stem cells Journal Article
In: NATURE, vol. 555, no. 7697, pp. E1-E17, 2018, ISSN: 0028-0836.
Molecular basis of functional myogenic specification of Bona Fide multipotent adult cardiac stem cells Journal Article
In: CELL CYCLE, vol. 17, no. 8, pp. 927-946, 2018, ISSN: 1538-4101.
Combining cell and gene therapy to advance cardiac regeneration Journal Article
In: EXPERT OPINION ON BIOLOGICAL THERAPY, vol. 18, no. 4, pp. 409-423, 2018, ISSN: 1471-2598.
Monographic issue of pharmacological research on adult myocardial repair/regeneration Journal Article
In: PHARMACOLOGICAL RESEARCH, vol. 127, pp. 1-3, 2018, ISSN: 1043-6618.
The use and abuse of Cre/Lox recombination to identify adult cardiomyocyte renewal rate and origin Journal Article
In: PHARMACOLOGICAL RESEARCH, vol. 127, pp. 116-128, 2018, ISSN: 1043-6618.
2017
Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification Journal Article
In: CELL DEATH AND DIFFERENTIATION, vol. 24, no. 12, pp. 2101-2116, 2017, ISSN: 1350-9047.
2016
C-kit expression is necessary but not sufficient to identify multipotent and robustly myogenic adult cardiac stem cells Inproceedings
In: pp. 517, 2016, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Rome, ITALY, AUG 27-31, 2016).
c-kit/CreERT2 knock-in allele does not efficiently fate-track c-kit positive resident cardiac stem cells and impairs their regenerative potential Inproceedings
In: pp. 835, 2016, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Rome, ITALY, AUG 27-31, 2016).
The heart has a constant and significant cardiomyocyte replacement rate by endogenous cardiac stem cells in the adult life Inproceedings
In: pp. 835, 2016, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Rome, ITALY, AUG 27-31, 2016).
Selective loss of adult cardiomyocytes is replenished by new endogenous cardiomyocyte formation in the presence of a patent coronary circulation Inproceedings
In: pp. 835-836, 2016, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Rome, ITALY, AUG 27-31, 2016).
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury Journal Article
In: CELL DEATH & DISEASE, vol. 7, 2016, ISSN: 2041-4889.
2015
In: pp. 45, 2015, ISSN: 1537-1891.
The adult myocardium has a robust endogenous cardiomyocyte turnover potential Inproceedings
In: pp. 60-61, 2015, ISSN: 1537-1891.
C-kit plus CSC-derived cardiomyocytes exhibit the typical transcriptional gene blueprint of adult cardiomyocytes Journal Article
In: VASCULAR PHARMACOLOGY, vol. 75, pp. 69, 2015, ISSN: 1537-1891.
Endogenous Cardiac Stem Cells' Activation in Response to Injury Potentiates Their Regenerative Ability Inproceedings
In: 2015, ISSN: 0009-7322, (Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association (AHA), Orlando, FL, NOV 07-11, 2015).
The adult myocardium has a robust endogenous cardiomyocyte turnover potential Inproceedings
In: pp. 611-612, 2015, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), London, ENGLAND, AUG 29-SEP 02, 2015).
c-kit/CreERT2 knock-in allele minimally tags c-kit positive resident endogenous cardiac stem cells and its cardiomyocyte progeny in the adult life Inproceedings
In: pp. 612, 2015, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), London, ENGLAND, AUG 29-SEP 02, 2015).
In situ activation of endogenous cardiac stem cells alters their secretome, miRnome, potentiating their regenerative capacity on the injured heart Inproceedings
In: pp. 612-613, 2015, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), London, ENGLAND, AUG 29-SEP 02, 2015).
c-kit plus CSC-derived cardiomyocytes exhibit the typical transcriptional gene blueprint of adult cardiomyocytes Inproceedings
In: pp. 950, 2015, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), London, ENGLAND, AUG 29-SEP 02, 2015).
Generation of new cardiomyocytes after injury: de novo formation from resident progenitors vs. replication of pre-existing cardiomyocytes Journal Article
In: ANNALS OF TRANSLATIONAL MEDICINE, vol. 3, no. 1, 2015, ISSN: 2305-5839.
Transcriptional profile of c-kit positive cardiac stem-progenitor cells (c-kitpos eCSCs) isolated from the four chambers of the adult human heart Inproceedings
In: pp. 31, 2015, ISSN: 0007-1323, (Annual Meeting of the Society-of-Academic-and-Research-Surgery (SARS(, Durham Univ, Durham, ENGLAND, JAN 07-08, 2015).
2014
In: CIRCULATION RESEARCH, vol. 115, no. 12, pp. E38-E39, 2014, ISSN: 0009-7330.
The cardiac stem cell compartment is indispensable for myocardial cell homeostasis, repair and regeneration in the adult Journal Article
In: STEM CELL RESEARCH, vol. 13, no. 3, B, pp. 615-630, 2014, ISSN: 1873-5061.
The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation Journal Article
In: EUROPEAN HEART JOURNAL, vol. 35, no. 39, SI, pp. 2722-2731, 2014, ISSN: 0195-668X.
Absence of Evidence Is Not Evidence of Absence Pitfalls of Cre Knock-Ins in the c-Kit Locus Journal Article
In: CIRCULATION RESEARCH, vol. 115, no. 4, pp. 415-418, 2014, ISSN: 0009-7330.
Understanding Tissue Repair Through the Activation of Endogenous Resident Stem Cells Book Chapter
In: Humana Press, Cham (Ed.): pp. 31-48, Humana Press, Cham, 2014, ISBN: 978-3-319-03572-7.
Protection against doxorubicine-induced cardiomyopathy by bergamot polyphenols through myocyte survival and cardiac stem cell activation Journal Article
In: CARDIOVASCULAR RESEARCH, vol. 103, no. 1, 2014, ISSN: 0008-6363, (3rd Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology, Barcelona, SPAIN, JUL 04-06, 2014).
Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy Journal Article
In: Journal of the American Heart Association, vol. 3, no. 2, pp. e000434, 2014.
2013
Adult c-kit(pos) Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair Journal Article
In: CELL, vol. 154, no. 4, pp. 827-842, 2013, ISSN: 0092-8674.
Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart Inproceedings
In: pp. 277, 2013, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Amsterdam, NETHERLANDS, AUG 31-SEP 04, 2013).
In: pp. E1141, 2013, ISSN: 0735-1097, (62nd Annual Scientific Session of the American-College-of-Cardiology, San Francisco, CA, MAR 09-11, 2013).