Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age. Diabetes, 2022 May 1;71(5):1081-1098. doi: 10.2337/db21-0536 Marino…
In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes. Communications Biology, volume 4, Article number: 1146 |…
Bernardo Nadal-Ginard, Eleonora Cianflone and Daniele Torella European Heart Journal, ehab335, Published: 21 June 2021. Heart failure (HF), the…
The paper received the editorial by Prof. Mark A. Sussman: ‘Atrial Myxoma: the cardiac chameleon’. European Heart Journal, ehaa208.
Abstract. An overdose of Isoproterenol (ISO) causes acute cardiomyocyte (CM) dropout and activates the resident cardiac c-kitpos stem/progenitor cells (CSCs) generating a burst of new CM formation that replaces those lost to ISO. Recently, unsuccessful attempts to reproduce these findings using c-kitCre knock-in (KI) mouse models were reported.
Kitcre knock-in mice fail to fate-map cardiac stem cells Carla Vicinanza, Iolanda Aquila, Eleonora Cianflone, Mariangela Scalise, Fabiola Marino, Teresa…